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. 2022 May;28(5):623–644. doi: 10.1261/rna.079019.121

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© 2022 Noller et al.; Published by Cold Spring Harbor Laboratory Press for the RNA Society

This article is distributed exclusively by the RNA Society for the first 12 months after the full-issue publication date (see http://rnajournal.cshlp.org/site/misc/terms.xhtml). After 12 months, it is available under a Creative Commons License (Attribution-NonCommercial 4.0 International), as described at http://creativecommons.org/licenses/by-nc/4.0/.

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FIGURE 2. — Distribution of C-values in 16S rRNAs. The number of sequences scoring each given C (conservation) value is shown for the 1961 sequences in our 16S rRNA database representing organisms across the entire phylogenetic spectrum. Note that the C-value 2.000 corresponds to bases that are universally conserved.