TABLE 2.

Classification of quinolones in the test gorup by use of the discriminant function obtained by LDA^a

Quinolone	M	Predicted activity
Active
PD116169	−5.34	−
PD118106	3.29	+
PD121960	0.39	+
PD122957	2.12	+
PD122958	0.66	+
PD123767	2.57	+
PD125353	3.91	+
PD126065	7.73	+
PD126592	2.24	+
PD127439	7.79	+
PD129603	4.23	+
PD131575	3.74	+
PD135346	6.13	+
PD138136	0.25	+
PD142198	5.61	+
PD143289	6.53	+
PD143471	2.14	+
PD160338	−2.69	−
PD160829	−1.65	−
PD161142	−1.60	−
PD161148	4.43	+
PD161317	5.07	+
PD161645	5.37	+
PD162287	5.86	+
PD163048	3.13	+
PD163049	1.98	+
PD163050	4.29	+
Inactive
PD109131	−0.10	−
PD111103	−4.26	−
PD111752	−0.41	−
PD114554	−4.71	−
PD115717	−7.14	−
PD116507	−7.75	−
PD116700	−6.07	−
PD120755	−5.20	−
PD129626	1.82	+
PD134545	−6.30	−
PD135305	4.88	+
PD135522	−4.39	−
PD136576	−0.86	−
PD141494	2.17	+
PD160352	−4.79	−
PD161141	−3.13	−
PD162278	−1.21	−

^aData for quinolones were obtained from Klopman et al. (20–22).