Table 2.

General electrophysiological parameters from recordings 1 and 3 d after administration of PEGPH20 or vehicle

	Condition
	Vehicle 1 d	Vehicle 3 d
Conduction	10.56 ± 1.99	6.71 ± 1.37
velocity	(n = 27)	(n = 21)
Mechanical threshold	2.77 ± 1.08	4.29 ± 1.52
(n = 9)	(n = 7)
Mechanical response	44.02 ± 18.57	108.80 ± 50.19
(peak IF, Hz)	(n = 9)	(n = 7)
Heat response	3.03 ± 0.95	4.7 ± 0.0
(peak IF, Hz)	(n = 2)	(n = 1)
Cold response	63.53 ± 18.53	34.90 ± 33.20
(peak IF, Hz)	(n = 2)	(n = 2)
Low metabolite response	13.4 ± 0.0	26.58 ± 23.24
(peak IF, Hz)	(n = 1)	(n = 4)
Hight metabolite response	1.39 ± 0.64	8.37 ± 6.19
(peak IF, Hz)	(n = 3)	(n = 4)
	Condition
	PEGPH20 1d	PEGPH20 3d
Conduction	6.487 ± 1.18	10.33 ± 1.92
velocity	(n = 24)	(n = 24)
Mechanical threshold	5.2 ± 1.11	1.92 ± 1.17
(n = 9)	(n = 7)
Mechanical response	77.41 ± 9.95	88.07 ± 31.53
(peak IF, Hz)	(n = 9)	(n = 7)
Heat response	26.7 ± 0.0	7.9 ± 1.5
(peak IF, Hz)	(n = 1)	(n = 2)
Cold response	No cold responses recorded	39.48 ± 18.73
(peak IF, Hz)	(n = 4)
Low metabolite response	3.9 ± 1.45	30.66 ± 12.09
(peak IF, Hz)	(n = 5)	(n = 7)
Hight metabolite response	13.16 ± 4.62	37.82 ± 14.05
(peak IF, Hz)	(n = 4)	(n = 5)

We do not observe any significant differences between electrophysiological recordings performed either 1 or 3 d after treatment in each condition.