FIGURE 3.

Activating transcription factor 3 (ATF3)/CCL2 axis mediates the TLR4/NF‐κB signaling. (a) Protein expression of TLR4, NF‐κB, ATF3 and CCL2 in brain tissues of rats with cerebral ischemia. (b) Protein expression of TLR4, NF‐κB, ATF3 and CCL2 in brain tissues of rats with cerebral ischemia after overexpression of ATF3/CCL2. Data are expressed as mean ± SD, and statistical significance was determined using two‐way analysis of variance (ANOVA), followed by Tukey multiple comparison test. *#p < .05