Fig. 2. Long-term effects of surgery conducted at different ages without estrogen therapy. Modeled cohorts of 10,000 patients undergoing hysterectomy and bilateral salpingo-oophorectomy or hysterectomy alone between age 45 and 55 years were simulated from surgery to 80 years. We report percent survival to 80 years and percent death from cardiovascular disease in E‒F, then report percent death from disease (subplots) in A‒D. The simulation uses age-specific baseline death rates and a posterior random sampling of 500 settings of hazard ratios for various interventions. Black dots represent the average of marginal statistics over 500 simulated cohorts, and bands show 95% Bayesian posterior intervals. Death from breast cancer (A), colon cancer (B), stroke (C), lung cancer (D), and cardiovascular disease (E) and survival (F).

Rush. Remodeling Ovary Removal at Hysterectomy. Obstet Gynecol 2022.