Table 5.
Comparison of parameters across the time points
| Parameters (A: Control group; B: Intervention group) | Baseline/Day 1 | Day 14 | Day 28 | P |
|---|---|---|---|---|
| A. IOP-r (mm hg) | 16 (13.95–18.65) | 16 (13.3–17.85) | 16.3 (13.85-18.55) | 0.627 |
| B. IOP-r (mm hg) | 16.26±2.98 | 15.54±2.81# | 15.24±3.1# | 0.001* |
| A. IOP-l (mm hg) | 16.08±3.57 | 16.22±3.69 | 16.43±4.08 | 0.733 |
| B. IOP-l (mm hg) | 15.95±3.1 | 15.36±2.6 | 15.4±3.1 | 0.114 |
| A. GQL-15 | 27.00 (20-39) | 28.50 (21-42.25) | 31.00 (19.75-40) | 0.547 |
| B. GQL-15 | 32.00 (20.75-46.25) | 29.50 (19-42.25) | 29.00 (20.75-41.25) | 0.786 |
| A. Average BREF | 64.25 (53-73.18) | 61.25 (53.25-69.18) | 57.62 (51.12-69.75) | 0.009* |
| B. Average BREF | 56.50 (53-72) | 59.25 (51.75-72) | 61.00 (58-75) | 0.166 |
| A. Cortisol | 254.76 (195.76-405.37) | 297.75 (194.37-366.35) | 226.19 (190.92-372.16) | 0.109 |
| B. Cortisol | 278.07 (192.3-394.25) | 225.69 (186.91-414.34) | 226.67 (182-31-358.75) | 0.618 |
| A. Beta endorphin | 117.76 (58.02-180.13) | 136.54 (73.09-401.98) | 117.76 (73.71-307.4) | 0.661 |
| B. Beta endorphin | 213.52 (46.49-416.44) | 178.0 (47.7-355.8) | 121.96 (58.86-355.81) | 0.577 |
| A. HR bpm | 75.32±12.09 | 78.08±12.84 | 79.87±11.67 | 0.022* |
| B. HR bpm | 76.50±11.49 | 77.59±10.033 | 75.76±9.32 | 0.519 |
| A. SBP (mm hg) | 122.89±12.66 | 120.92±11.75 | 123.34±13.27 | 0.229 |
| B. SBP (mm hg) | 128.29±14.8 | 129.97±15.58 | 127.09±14.69 | 0.145 |
| A. DBP (mm hg) | 79.29±8.85 | 76.11±10.17 | 77.95±10.04 | 0.255 |
| B. DBP (mm hg) | 80.53±7.48 | 79.15±7.47 | 79.5±8.33 | 0.535 |
| A. FBG (mg/dl) | 97.13 (87.35-106.32) | 96.50 (89-106.04) | 97.03 (89-111.23) | 0.323 |
| B. FBG (mg/dl) | 89.25 (81.21-112.96) | 95.05 (84.7-112.06) | 92.98 (84.71-102.7) | 0.278 |
| A. Weight (kg) | 60.65 (55.6-70.37) | 60.40 (55.4-70.45) | 60.25 (55.62-70.8) | 0.963 |
| B. Weight (kg) | 67.45 (59.7-80.4) | 67.85 (59.65-82.65) | 66.95 (60.05-79.75) | 0.399 |
| A. BMI (kg/sqm) | 25.0 (23.01-27.16) | 25.0 (22.97-27.12) | 25.00 (22.98-27.17) | 0.880 |
| B. BMI (kg/sqm) | 27.06 (23.23-29.15) | 27.03 (23.26-29.62) | 26.98 (23.18-29.11) | 0.279 |
*P value found <0.05. #Significantly different from the baseline value. Repeated measure ANOVA presented as mean±SD and Friedman test results are presented as median (Q1-Q3; Bonferroni post hoc test applied for B. IOP-r and A. Average BREF). SD=Standard deviation, IOP=Intraocular pressure, IOP-r=IOP of right, IOP-l=IOP of left, GQL-15=Glaucoma quality of life-15, HR=Heart rate, BP=Blood pressure, SBP=Systolic BP, DBP=Diastolic BP, BMI=Body mass index, FBG=Fasting plasma glucose, Q1=First quartile, Q3=Third quartile