Table 1.
Baseline characteristics of the participants compared by independent t-test.
| Parameter | S.L. group (n=125) | OCH group (n=125) | p-value | |
|---|---|---|---|---|
| Age | 46.83±15.24 | 40.24±14.7 | 0.001 | |
| Gender | Male | 1 (0.8%) | 0 (0%) | 0.113 |
| Female | 89 (71.2%) | 102 (81.6%) | ||
| Clinical and radiological findings | ||||
| Fever | 71 (56.8%) | 75 (60.0%) | 1 | |
| Sore Throat | 3 (2.4%) | 5 (4.0%) | 1 | |
| Dyspnea | 21 (16.8%) | 21 (16.8%) | 1 | |
| Cough | 69 (55.2%) | 59 (47.2%) | 0.071 | |
| Pneumonia | 90 (72.0%) | 58 (46.4%) | 0.003 | |
| ECG abnormal | 29 (23.2%) | 35 (28.0%) | 0.591 | |
| ECG Findings | Normal | 90 (72.0%) | 49 (39.2%) | <0.001 |
| T Wave | 7 (5.6%) | 3 (2.4%) | ||
| QT Segment | 6 (4.8%) | 13 (10.4%) | ||
| Other | 16 (12.8%) | 19 (15.2%) | ||
| CT Chest | Scattered Opacities | 60 (48.0%) | 48 (38.4%) | <0.001 |
| Consolidated Patches | 5 (4.0%) | 6 (4.8%) | ||
| GG appearance | 37 (29.6%) | 65 (52.0%) | ||
| Unremarkable | 0 (0.0%) | 0 (0.0%) | ||
| Lower Lobe Pneumonia Patch | 10 (8.0%) | 6 (4.8%) | ||
| Scattered Pneumonia | 13 (10.4%) | 0 (0.0%) | ||
| Laboratory findings | ||||
| Total Leukocyte Count | 5.92±5.68 | 5.71±2.37 | 0.720 | |
| Neutrophils count | 60.28±13.00 | 58.69±14.94 | 0.384 | |
| Lymph | 33.87±10.93 | 35.80±14.15 | 0.239 | |
| Neutrophil lymphocyte ratio | NI | 204.61±73.68 | - | |
| Platelet count | 209.29±85.68 | NI | - | |
| Alanine transaminase | 35.88±29.19 | 29.62±13.28 | 0.041 | |
| Urea | 33.27±14.88 | 1.13±0.31 | <0.001 | |
| Creatinine | 1.15±0.43 | 30.38±19.82 | <0.001 | |
| C-reactive protein | NI | 318.18±331.22 | - | |
| D-dimer | 357.75±443.92 | 136.33±140.27 | 0.019 | |
| Serum ferritin | 386.37±510.42 | 195.80±323.49 | 0.110 | |
| Thyroglobulin | 186.13±102.17 | 219.39±92.63 | 0.177 | |
| Lactate dehydrogenase | 255.76±90.90 | 70.80±132.85 | <0.001 | |
| Fibrinogen | 343.14±84.16 | 261.60±123.65 | 0.152 | |
SL group – Sofosbuvir plus Ledipasvir; OCH group – Oseltamivir plus Hydroxychloroquine combined with Azithromycin. Data were represented as mean±SD or frequency (percentage). NI – no information.