Table 1.
Age-Adjusted Baseline Characteristics of Participates by Status of a History of Gallstone disease
| NHS | HPFS | |||
|---|---|---|---|---|
| History of gallstone disease | No | Yes | No | Yes |
| Participants No. | 78,928 | 7102 | 42,533 | 1416 |
| Age (years) * | 45.9(7.2) | 48.1(7.0) | 53.5(9.5) | 59.9(9.2) |
| White (%) | 97.5 | 98.4 | 90.9 | 91.2 |
| Married (%) | 91.4 | 90.5 | 90.2 | 90.7 |
| Body Mass Index (kg/m2) | 24.1(4.3) | 26.7(5.7) | 25.5(3.3) | 26.7(3.8) |
| Physical activity (metabolic equivalent/week) | 14.2(20.3) | 12.4(18.8) | 21.3(29.6) | 16.9(24.1) |
| Premenopausal (%) | 56.9 | 49.4 | - | - |
| Current use of postmenopausal hormone (%) | 8.2 | 11.2 | - | - |
| Current smoker (%) | 28.5 | 31.7 | 9.7 | 11.7 |
| Current alcohol drinker (%) | 69.1 | 62.6 | 76.8 | 70.8 |
| Alcohol (g/day) | 6.5(10.6) | 4.9(9.3) | 11.5(15.6) | 8.4(12.2) |
| Hypertension (%) | 15.0 | 24.3 | 20.0 | 25.0 |
| Hypercholesterolemia (%) | 5.0 | 7.6 | 10.4 | 13.2 |
| Family history of myocardial infarction ≤ 60 years (%) | 18.8 | 21.9 | 12.0 | 11.7 |
| Family history of diabetes (%) | 27.9 | 35.7 | 19.2 | 22.6 |
| Family history of cancer (%) | 16.0 | 15.4 | 15.4 | 16.2 |
| Regular Aspirin user (%) | 40.0 | 43.5 | 26.6 | 28.7 |
| Daily energy intake (kcal/day) | 1566.4(500.1) | 1562.9(515.8) | 1994.8(620.5) | 1991.6(645.8) |
| Daily cholesterol intake (mg/day) | 336.5(122.1) | 336.5(126.4) | 305.2(111.2) | 306.9(100.7) |
| Alternative Health Eating Index Score | 42.7(10.2) | 42.1(10.1) | 46.7(10.8) | 45.7(11.6) |
Values are means (SD) or percentages and are standardized to the age distribution of the study population.
*
Value is not age adjusted.