Table 2.
Comparison of laboratory parameters on Day 5 of treatment between the groups
| Group 1 (n = 60), mean ± SD | Group 2 (n = 60), mean ± SD | Group 3 (n = 60), mean ± SD | p | |
|---|---|---|---|---|
| WBC (/µl) | 8602. 3 ± 2676.9 | 8352.7 ± 2538.2 | 8895.1 ± 3867.8 | 0.51 |
| Lymphocytes (/µl) | 1102. 4 ± 874.2 | 1283.7 ± 857.6 | 1305.9 ± 733.3 | 0.85 |
| Neutrophils (/µl) | 6643.1 ± 2403.4 | 6485.7 ± 2110.2 | 7063.8 ± 3786.8 | 0.46 |
| Eosinophils (/µl) | 12.4 ± 20.1 | 11.7 ± 28.8 | 13.8 ± 26.1 | 0.76 |
| Hemoglobin (g/L) | 13.4 ± 1.1 | 13.1 ± 1.8 | 13.6 ± 2.1 | 0.52 |
| Platelets (/µl) | 268 920.1 ± 101 000 | 2 783 66.7 ± 96 432.1 | 281 750 ± 119 759.7 | 0.85 |
| MPV (fl) | 10.7 ± 0.7 | 10.8 ± 1.2 | 10.3 ± 0.8 | 0.09 |
| AST (U/L) | 31.4 ± 30.1 | 33.8 ± 32.7 | 28.4 ± 12.7 | 0.38 |
| ALT (U/L) | 58.4 ± 40.4 | 60.2 ± 44.7 | 45.9 ± 28.5 | 0.15 |
| GGT (U/L) | 72.4 ± 60.2 | 80.6 ± 96.2 | 52.1 ± 52.3 | 0.21 |
| ALP (U/L) | 71.4 ± 60.4 | 85.9 ± 58.9 | 66.8 ± 23.6 | 0.1 |
| LDH (U/L) | 301.4 ± 120.4 | 227.9 ± 60.2 | 269.8 ± 106.9 | 0.04a |
| Total protein (g/l) | 58.9 ± 10.4 | 61.9 ± 7.4 | 59.9 ± 6.3 | 0.45 |
| Albumin (g/l) | 39.7 ± 9.5 | 40.8 ± 6.6 | 39.6 ± 4.9 | 0.36 |
| Total bilirubin (mg/dl) | 0.6 ± 0.2 | 0.5 ± 0.3 | 0.6 ± 0.3 | 0.61 |
| Direct bilirubin (mg/dl) | 0.3 ± 0.2 | 0.2 ± 0.1 | 0.2 ± 0.1 | 0.78 |
| Ferritin (ng/ml) | 410.4 ± 214.6 | 345.2 ± 355.7 | 289.2 ± 292.8 | 0.5 |
| Fibrinogen (ng/ml) | 510.4 ± 110.1 | 405.4 ± 109.4 | 332.4 ± 72.1 | 0.002a |
| 0.02b | ||||
| D‐dimer (ng/ml) | 678.3 ± 300.4 | 589.7 ± 527.1 | 476.4 ± 205.7 | 0.05a |
| Troponin‐ı (ng/dl) | 4.1 ± 3.2 | 3.3 ± 1.9 | 4.4 ± 5.5 | 0.21 |
| INR | 1.2 ± 0.9 | 1.1 ± 0.1 | 1.1 ± 0.3 | 0.31 |
| PT (s) | 14.4 ± 1.7 | 13.8 ± 1.5 | 14.1 ± 2.1 | 0.44 |
| aPTT (s) | 28.4 ± 4.4 | 27.8 ± 2.8 | 28.9 ± 3.1 | 0.36 |
| CRP (mg/l) | 30.4 ± 20.4 | 12.6 ± 11.3 | 16.8 ± 18.3 | 0.03a |
| Procalcitonin (ng/ml) | 0.8 ± 0.5 | 0.3 ± 0.4 | 0.4 ± 0.4 | 0.04a |
Abbreviations: ALP, alkaline phosphatase; ALT, alanine aminotransferase; aPTT, activated partial thromboplastin time; AST, aspartate aminotransferase; GGT, γ‐glutamyl transferase; INR, international normalized ratio; LDH, lactate dehydrogenase; MPV, mean platelet volume; PT, prothrombin time; WBC, white blood cells.
a
Groups 2 and 3 versus Group 1.
b
Group 2 versus Group 3.