TABLE 3.
Multivariable HRs for the risk of overall or COVID‐19‐related death in postvaccination versus unvaccinated COVID‐19
| Variable | Overall death | COVID‐19‐related death | ||
|---|---|---|---|---|
| aHR (95% CI) | p | aHR (95% CI) | p | |
| Number of patients | 762 | – | 762 | – |
| Number of events | 87 | – | 64 | – |
| Group | ||||
| Control | REF | REF | ||
| Vaccine | 0.21 (0.10–0.42) | <0.0001 | 0.23 (0.10–0.53) | 0.0005 |
| Location, n (%) | ||||
| Northeast | REF | REF | ||
| Southeast | 1.22 (0.56–2.65) | 0.6128 | 1.55 (0.61–3.93) | 0.3524 |
| Midwest | 1.28 (0.62–2.62) | 0.5038 | 1.47 (0.61–3.53) | 0.3863 |
| South | 0.64 (0.27–1.49) | 0.2974 | 0.83 (0.30–2.30) | 0.7158 |
| Northwest | 1.97 (0.79–4.90) | 0.1435 | 2.00 (0.66–6.04) | 0.2209 |
| Southwest | 1.56 (0.71–3.44) | 0.2671 | 2.23 (0.90–5.53) | 0.0841 |
| Age | 1.05 (1.02–1.08) | 0.0002 | 1.06 (1.03–1.09) | 0.0003 |
| BMI | 1.00 (0.97–1.03) | 0.7580 | 1.01 (0.98–1.04) | 0.5361 |
| Diabetes | ||||
| No | REF | REF | ||
| Yes | 1.07 (0.65–1.74) | 0.7991 | 0.90 (0.52–1.55) | 0.7084 |
| Alcohol | ||||
| No | REF | REF | ||
| Yes | 1.05 (0.63–1.75) | 0.8453 | 1.16 (0.66–2.04) | 0.6173 |
| AUDIT‐C score | ||||
| Low | REF | REF | ||
| High | 1.08 (0.54–2.15) | 0.8289 | 1.05 (0.47–2.33) | 0.9112 |
| eCTP | ||||
| A | REF | REF | ||
| B | 1.18 (0.67–2.09) | 0.5588 | 0.99 (0.51–1.92) | 0.9689 |
| C | 1.08 (0.19–6.10) | 0.9288 | N/A | N/A |
| Dexamethasone | ||||
| No | REF | REF | ||
| Yes | 4.43 (2.27–8.65) | <0.0001 | 3.79 (1.68–8.57) | 0.0014 |
| Remdesivir | ||||
| No | REF | REF | ||
| Yes | 0.62 (0.29–1.33) | 0.2229 | 1.13 (0.47–2.71) | 0.7836 |
| MELD‐Na | 1.03 (0.99–1.08) | 0.1592 | 1.03 (0.98–1.09) | 0.2445 |
Bold indicates significance.
Abbreviations: N/A, not available; REF, reference.