Table 1.
Characteristics of the patients
| Non–COVID‐19 (n = 52) | COVID‐19 (n = 52) | P value | |
|---|---|---|---|
| Age, years | 60 (51–72) | 61 (56–71) | 0.197 |
| Sex, female/male | 13/39 | 13/39 | 1.00 |
| Adm BW, kg | 77 (63–90) | 85 (75–97) | 0.001 |
| Ideal BW, kg | 67 (61–72) | 70 (61–75) | 0.453 |
| Height, m | 1.72 (1.67–1.80) | 1.74 (1.68–1.80) | 0.345 |
| BMI, kg/m2 | 25.05 (21.07–31.48) | 27.72 (25.57–33.75) | 0.003 |
| Obesity (≥30), n (%) | 15 (28.9) | 20 (38.5) | 0.300 |
| Discharge BW, kg | 72.0 (57.0–84.4) | 86.0 (72.5–95.5) | 0.001 |
| Weight loss, kg | 4.0 (0.5–9.2) | 2.5 (0–6.7) | 0.513* |
| McCabe score | 0.002 | ||
| Nonfatal | 30 | 45 | |
| Fatal 5 years | 19 | 7 | |
| Fatal 6 months | 3 | 0 | |
| SAPS II | 41 (33–59) | 40 (33–46) | 0.138 |
| SOFA Adm score | 8 (6–11.2) | 7 (5–8) | 0.013 |
| Length of mech. vent., days | 15.5 (10.3–21.8) | 16.5 (11.6–22.8) | 0.422 |
| Patients on CRRT, n (%) | 14 (26.9) | 7 (13.5) | 0.059 |
| Length ICU stay, days | 26.6 (21.0–40.9) | 20.3 (15.8–29.0) | 0.030 |
| Length of hospital stay, days | 52.9 (27.4–79.7) | 29.04 (23.39–40.7) | <0.0001 |
| ICU mortality, n (%) | 10 (19.2) | 8 (15.4) | 0.604 |
| Hospital mortality, n (%) | 13 (25.0) | 9 (17.3) | 0.336 |
| Metabolic variables | |||
| Diabetes preadmission | 16/52 | 11/52 | 0.650 |
| NRS | 5 (4–6) | 5 (4–6) | 0.742 |
| NRS‐A‐food intake (median (IQR) (mean ± SD) | 1.5 (0–3) (1.4 ± 1.2) | 2 (1–3) (1.8 ± 1.0) | 0.089 |
| NRS ≥ 5, n (%) | 34 (65.4) | 35 (67.3) | 0.6338 |
| Harris‐Benedict, kcal | 1560 (1295–1158) | 1647 (1482–1863) | 0.007 |
| Energy goal of 20 kcal/kg/day | 1530 (1260–1800) | 1700 (1505–1930) | 0.001 |
| Time to feeding, days (median (IQR)) | 1.0 (0–2.0) | 0.5 (0–1.0) | <0.0001 |
| Mean ± SD | 1.33 ± 1.24 | 0.52 ± 0.54 | |
| CRP (Adm), mg/L | 108 (42–214) | 202 (130–283) | 0.003 |
| Prealbumin (Adm), g/L | 0.095 (0.07–0.14) | 0.070 (0.06–0.09) | 0.014 |
| Delta prealbumin, g/L | 0.025 (0.01–0.06) | 0.19 (0.09–0.32) | <0.0001 |
Note: Data are presented as median (IQR) unless described otherwise.
Abbreviations: Adm, admission; BMI, body mass index; BW, body weight; COVID‐19, coronavirus disease 2019; CRP, C‐reactive protein; CRRT, continuous renal replacement therapy; ICU, intensive care unit; mech. vent., mechanical ventilation; NRS, Nutrition Risk Screening; SAPS II, Simplified Acute Physiology Score; SOFA, Sequential Organ Failure Assessment.
*
Significant weight loss (P < 0.0001) but similar and parallel in both groups.