Table 2.

Serum concentrations and activities of oxidative stress markers, results are expressed as mean ± SD

	Marker	Healthy control	Mild disease	Severe disease	p value
Anti‐oxidants variables	TAC (μM/L)	0.28 ± 0.11	0.14 ± 0.03	0.06 ± 0.02	<0.001
	SOD (u/ml)	26.11 ± 12.47	23.52 ± 8.49	20.75 ± 7.08	0.5
	CAT (u/ml)	29.60 ± 7.16	29.43 ± 5.53	27.84 ± 8.44	0.3
Oxidant marker	NO (μmol/ml)	36.08 ± 15.02	35.95 ± 11.86	35.75 ± 12.77	0.9

Note: The p value compares severe disease, healthy controls, and mild disease groups. Statistical significances (ANOVA and Kruskal–Wallis test) were only seen in the case of TAC among the three studied groups.

Abbreviations: CAT, catalase; NO, nitric oxide; SOD, superoxide dismutase; TAC, total antioxidant capacity.