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. 2022 Jan 18;94(5):2026–2034. doi: 10.1002/jmv.27579

Table 2.

Comparison of pulmonary function test results, saturation levels, and heart rate in postacute COVID‐19 patients at 4 and 12 weeks

Group 1 (n = 83) Group 1 (n = 83) Group 2 (n = 34) Group 2 (n = 34) Group 3 (n = 34) Group 3 (n = 34)
Mean ± SD Mean ± SD Mean ± SD Mean ± SD Mean ± SD Mean ± SD
Week 4  Week 12 Week 4 Week 12 Week 4 Week 12 p* p**
FVC% 111 ± 22.8 114.3 ± 17.4 109.1 ± 15.5 111.9 ± 15.2 91.3 ± 21.4 a,b* 97.4 ± 22.7 a,b** <0.001 0.002
FEV1% 106.5 ± 21.1 108.1 ± 20.3 104.3 ± 23.3 104.5 ± 16.1 91.6 ± 19.1 a,b* 96 ± 21.2 a** 0.004 0.03
FEF25‐75% 81.47 ± 29.3 84.1 ± 27.9 88.3 ± 37.2 89.2 ± 30.9 81 ± 23.5 86.1 ± 24.9 0.73 0.35
DLCO/VA% 115.1 ± 23.8 120.2 ± 18.8 111.7 ± 18.1 112.8 ± 16.5 89.2 ± 21.1 a,b* 103.9 ± 13.6 a** <0.001 <0.001
SO2 (%) 93.1 ± 4.5 94 ± 2.7 92.3 ± 3.8 93.1 ± 1.3 87.1 ± 6.4 a,b* 91.3 ± 4.7 a** <0.001 0.02
Heart rate (beats/min) 90.6 ± 11.5 88.9 ± 12.5 98.5 ± 10.5 90.1 ± 8.6 104.2 ± 11.3a* 104.1 ± 11.5a,b** <0.001 <0.001

Note: Wilcoxon test was used for within‐group comparisons of laboratory parameters and Weeks 4 and 12 (bold indicate statistically significant); Kruskal–Wallis test was used for between‐group comparisons of Week 4 and Week 12 data (p*: comparison of Week 4 data, p**: comparison of Week 12 data, p a: comparison with group 1, p b: comparison between groups 2 and 3).

Abbreviations: %, percent predicted; FVC, forced vital capacity; FEV1, forced expiratory volume in 1 s; DLCO/VA, diffusing capacity divided by the alveolar volume.