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. 2022 Apr 4;10:838785. doi: 10.3389/fcell.2022.838785

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Copyright © 2022 Chu, Wang, Zhang, Liu, Sun, Liang, Zhang, An, Wei, Zhu, Guo, Zhao, Fu, Xu and Li.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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miR-513c-5p targets caspase-1 mRNA 3′UTR directly. (A) Schematic representation of caspase-1 mRNA 3′UTR demonstrating putative miRNA target site, luciferase activities of WT and Mut constructs. (B,C) The luciferase activity was determined by co-transfecting the vectors (caspase-1 3′UTR-WT or Mut) combined with NC, miR-513c-5p mimics into 293T cells, respectively. ****p < 0.0001.