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. 2022 Apr 18;247:29–37.e7. doi: 10.1016/j.jpeds.2022.04.032

Figure 4.

Figure 4

SIR of SARS-CoV-2 among household contacts, by age and SARS-CoV-2 lineage of primary cases, California and Colorado, January to April 2021. To account for household clustering, ORs and 95% CIs were calculated using GEEs with an exchangeable correlation matrix and used to compare the SIRs of the primary case to assess transmission risk (the probability of transmission from the primary case to household contacts) by age group (pediatric vs adult) and lineage group (B.1.1.7 [Alpha] vs non-Alpha). Four pediatric and 45 adult household contacts reported prior SARS-CoV-2 infection or seropositivity and were excluded from the SIR calculations. Specimens from 5 primary pediatric cases did not undergo sequencing; therefore, a lineage was not assigned to these individuals.