Figure 3.

Symptoms of COVID-19 among pediatric household cases by SARS-CoV-2 lineage (n = 92). A, Frequency of symptoms by lineage. B, ORs and 95% CIs for the presence of symptoms, comparing pediatric cases with B.1.1.7 (Alpha) lineage (n = 60) to pediatric cases with non-Alpha lineages (n = 32). ^aSymptoms were categorized as constitutional (measured or subjective fever, chills, myalgia, and fatigue), upper respiratory (runny nose, nasal congestion, and sore throat), lower respiratory (cough, difficulty breathing, shortness of breath, wheezing, and chest pain), neurologic (headache, loss of taste, and loss of smell), and gastrointestinal (nausea and/or vomiting, diarrhea, and abdominal pain). ^bUnadjusted ORs and 95% CIs were estimated using generalized estimated equations with an exchangeable correlation matrix to account for household clustering. ORs and 95% CIs were graphed on a log scale.