Effects of different fractions of Tamarindus indica (n-hexane, dichloromethane, and ethyl acetate) using a T-maze test on Alzheimer's disease-induced ratsa.
| Baseline | Induction (two months) | Treatment (6 weeks) | |
|---|---|---|---|
| Control | 16.00 ± 1.00a | 17.00 ± 1.00a | 16.60 ± 0.34a |
| AlCl3-AD | 19.40 ± 0.67b | 45.78 ± 0.67c | — |
| % Change | +21.25 | +169.29 | — |
| n-Hexane | — | — | 26.50 ± 1.65d |
| % Improvement | 116.14 | ||
| Dichloromethane | — | — | 29.00 ± 1.71d |
| % Improvement | 101.10 | ||
| Ethyl acetate | — | — | 20.00 ± 1.22e |
| % Improvement | 155.30 | ||
| Donepezil drug | — | — | 25.08 ± 1.60d |
| % Improvement | 124.69 |
a
Data are expressed in seconds as mean ± SD (n = 8). Groups with similar letters are not significantly different, while those with different letters are significantly different at p ≤ 0.05.