Skip to main content
. 2022 Apr 19;12(19):11769–11785. doi: 10.1039/d2ra01340a

Effect of different fractions of Tamarindus indica (n-hexane, dichloromethane, and ethyl acetate) on tau protein and amyloid-β proteins in Alzheimer's disease-induced ratsa.

Parameter Control AlCl3-AD n-Hexane Dichloromethane Ethyl acetate Donepezil drug
Tau protein (ng L−1) 310.00 ± 12.00a 1100.00 ± 29.45b 512.00 ± 23.55d 621.00 ± 30.18c 422.50 ± 21.22e 478.01 ± 34.90e
% Change 254.83 65.16 100.32 36.12 54.19
% Improvement 189.67 154.52 218.70 200.64
Amyloid β (g L−1) 665.00 ± 39.10h 1445.50 ± 32.80i 756.00 ± 22.23j 870.00 ± 30.10j 758.10 ± 3.12j 834.19 ± 17.02j
% Change 117.29 13.68 30.82 13.98 25.44
% Improvement 103.60 86.46 103.30 91.87
a

Data are expressed as mean ± SD (n = 8). Groups with similar letters are not significantly different, while those with different letters are significantly different at p ≤ 0.05.