Effect of different fractions of Tamarindus indica (n-hexane, dichloromethane, and ethyl acetate) on tau protein and amyloid-β proteins in Alzheimer's disease-induced ratsa.
Parameter | Control | AlCl3-AD | n-Hexane | Dichloromethane | Ethyl acetate | Donepezil drug |
---|---|---|---|---|---|---|
Tau protein (ng L−1) | 310.00 ± 12.00a | 1100.00 ± 29.45b | 512.00 ± 23.55d | 621.00 ± 30.18c | 422.50 ± 21.22e | 478.01 ± 34.90e |
% Change | 254.83 | 65.16 | 100.32 | 36.12 | 54.19 | |
% Improvement | 189.67 | 154.52 | 218.70 | 200.64 | ||
Amyloid β (g L−1) | 665.00 ± 39.10h | 1445.50 ± 32.80i | 756.00 ± 22.23j | 870.00 ± 30.10j | 758.10 ± 3.12j | 834.19 ± 17.02j |
% Change | 117.29 | 13.68 | 30.82 | 13.98 | 25.44 | |
% Improvement | 103.60 | 86.46 | 103.30 | 91.87 |
Data are expressed as mean ± SD (n = 8). Groups with similar letters are not significantly different, while those with different letters are significantly different at p ≤ 0.05.