Table.2.
IGSC 20% dose and infusion characteristics in the safety populationa
| Median (interquartile range) | Mean (SD) | |
|---|---|---|
| Weekly dose per infusion, mg/kg | 113.0 (106.3–144.7) | 125.5 (28.46) |
| Volume per infusion, mL | 35.5 (25.4–48.6) | 37.0 (17.20) |
| Duration per infusion, hours | 1.00 (0.77–1.53) | 1.15 (0.57) |
| Infusion sites per infusion,b n | 2.0 | 2.0 (0.75) |
| Volume infused per site per infusion, mL/site | 19.0 (14.14–24.46) | 19.3 (7.64) |
| Infusion rate per site per infusion, mL/h/site | 21.0 (13.73–26.27) | 20.0 (9.29) |
| Dose conversion factorc | 1.000 (0.96–1.17) | 1.065 (0.162) |
SD, standard deviation
a3044 infusions in 61 subjects
bSince the number of infusion sites must be an integer, the interquartile range was not calculated
cIGSC 20% weekly dose/weekly dose equivalent of previous IgG regimen