Fig. 1.

Network pharmacological prediction for KXS treatment of AD. a Compound-disease-target networks of KXS against AD. The rectangle nodes represent ingredients of herbs (orange for PO, purple for GR, green for AT, pink for PR, and red for Multidrugs-GR and PO), and the yellow ellipse nodes represent targets. b Protein-protein interactions identified by STRING software. c GO enrichment analysis of the intersecting targets’ biological process. d KEGG pathway enrichment analysis. e Target-pathway networks for KXS treatment of AD. The blue nodes represent the related pathways, and the ellipse nodes represent potential targets. The color depth and size of nodes are in proportion to their degree