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. 2022 Apr 18;13(4):361. doi: 10.1038/s41419-022-04818-5

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© The Author(s) 2022

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 6 — A KYSE-150 cells with indicated modifications were subcutaneously injected into the flanks of mice in the armpit. Subcutaneous xenograft tumors, as well as changes in tumor size, are displayed. B TE-1 cells with indicated modifications were subcutaneously injected from the tail vein of nude mice. The lung tissues of the mice were harvested, and the number of metastatic foci was counted. C, D Indicated proteins were detected by IHC assays in murine tissues. The representative images are presented. E Detection of circFAM120B expression in eight pairs of plasma samples from ESCC patients and healthy volunteers by qRT-PCR analysis. F Assessment of PPM1L expression in 96 pairs of ESCC tissues by qRT-PCR analysis. G Correlation between circFAM120B and PPM1L expression in 96 pairs of ESCC tissues.