Fig. 7.

Results of the network meta-analysis for safety outcomes. In the network diagrams, the thickness of the edge connections represent the relative number of direct connections between the connected nodes, and shaded triangles represent multi-arm trials. In the forest diagrams, treatments were ranked from the most efficacious (i.e., the highest P score) to the least efficacious (i.e., the lowest P score), with ORs < 1 indicating beneficial treatment effects compared to SOC. A The network diagram for incidence of adverse events. B The forest diagram showing pooled ORs within each treatment arm compared to SOC for incidence of adverse events. C The network diagram for incidence of serious adverse events. D The forest diagram showing pooled ORs within each treatment arm compared to SOC for incidence of serious adverse events. SOC standard of care, IVIg intravenous immune globulin, OR odds ratio, CI confidence interval