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. 2022 Mar 29;98(3):222–227. doi: 10.1136/sextrans-2021-055352

Table 2.

Summary estimates for associations between Mycoplasma genitalium in pregnancy and adverse pregnancy and perinatal outcomes

Outcome, study design Analysis Number of studies, design Sample size for outcome I2 % Summary OR
(95% CI)
Preterm birth Unadjusted, meta-analysis 7
5 cohort, 2 case–control
4573 0 1.91 (1.29 to 2.81)
Adjusted, meta-analysis 2
1 cohort, 1 case–control
NR 0 2.34 (1.17 to 4.71)
Spontaneous abortion Unadjusted, meta-analysis 6
4 cohort, 2 case–control
2837 0 1.00 (0.53 to 1.89)
Adjusted 1 case–control 216 NA 0.9 (0.2 to 3.8)*
Premature rupture of membranes Unadjusted 1 cohort 871 NA 7.62 (0.40 to 145.86)
Low birth weight Unadjusted 1 cohort 81 NA 1.07 (0.02 to 10.39)
Perinatal death Unadjusted 1 cohort 872 NA 38.42 (1.45 to 1021.43)
Unadjusted 1 case–control 725 NA 1.07 (0.49 to 2.36)

*Adjusted OR reported to one decimal place, as in the publication, reference 25.

NA, not applicable; NR, not reported.