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. 2022 Feb 8;93(5):481–490. doi: 10.1136/jnnp-2021-327462

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© Author(s) (or their employer(s)) 2022. Re-use permitted under CC BY. Published by BMJ.

This is an open access article distributed in accordance with the Creative Commons Attribution 4.0 Unported (CC BY 4.0) license, which permits others to copy, redistribute, remix, transform and build upon this work for any purpose, provided the original work is properly cited, a link to the licence is given, and indication of whether changes were made. See: https://creativecommons.org/licenses/by/4.0/.

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Topographical segmentation of white matter hyperintensity (WMH) burden. WMH volumes were quantified into (A) lobar regions (frontal, temporal, parietal, occipital) and (B) periventricular and deep WMH.