Table 3.
Hazard ratios for development of individual cancer entities by CAC score group
| Cancer types | CAC score groups, HR (95% CI) |
||||
|---|---|---|---|---|---|
| CAC = 0 | CAC 1–99 | CAC 100–399 | CAC ≥ 400 | Log(CAC + 1) | |
| Breast (n = 60) | |||||
| Unadjusted | Ref. | 1.12 (0.59–2.14) | 1.25 (0.52–3.00) | 2.76 (1.15–6.63) | 1.10 (0.98–1.23) |
| Adjusteda | Ref. | 0.98 (0.48–2.02) | 0.83 (0.32–2.15) | 1.91 (0.70–5.22) | 1.04 (0.98–1.05) |
| Prostate (n = 155) | |||||
| Unadjusted | Ref. | 1.73 (1.16–2.56) | 1.60 (1.01–2.56) | 1.89 (1.17–3.06) | 1.10 (1.04–1.17) |
| Adjusteda | Ref. | 1.53 (1.01–2.31) | 1.11 (0.64–1.90) | 1.17 (0.68–2.02) | 1.03 (0.96–1.10) |
| Colorectal (n = 71) | |||||
| Unadjusted | Ref. | 1.35 (0.77–2.39) | 1.35 (0.66–2.77) | 2.32 (1.16–4.64) | 1.09 (0.99–1.21) |
| Adjusteda | Ref. | 1.02 (0.59–1.77) | 0.77 (0.36–1.67) | 1.22 (0.58–2.53) | 1.00 (0.90–1.10) |
| Lung (n = 115) | |||||
| Unadjusted | Ref. | 1.52 (0.91–2.55) | 3.83 (2.36–6.21) | 4.87 (2.92–8.13) | 1.27 (1.19–1.37) |
| Adjusteda | Ref. | 1.44 (0.83–2.49) | 3.34 (1.88–5.94) | 3.22 (1.61–6.46) | 1.22 (1.11–1.34) |
a
Adjusted for: age, sex, race, body mass index, physical activity, income >40K, completed high school, health insurance, pack-years of smoking, healthy diet.
CAC, coronary artery calcium score; CI, confidence interval; HR, hazard ratio.