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. 2022 Apr 18;12(4):e057999. doi: 10.1136/bmjopen-2021-057999

Table 5.

Diseases and disorders associated with the brain by demographic groups

Variable Characteristics AD and dementia Schizophrenia Depression
% OR 99% CI % OR 99% CI % OR 99% CI
Gender Women 99.4 96.4 95.6
Men 98.5 0.40 0.29 to 0.56 94.5 0.64 0.54 to 0.75 93.8 0.70 0.60 to 0.81
Other/undisclosed 100 95.2 0.74 0.25 to 2.18 96.0 1.11 0.34 to 3.61
Age (years) >60 99.3 95.1 94.2
41–60 99.4 1.08 0.71 to 1.65 96.6 1.47 1.23 to 1.75 96.1 1.51 1.29 to 1.78
<40 98.0 0.35 0.23 to 0.51 96.3 1.34 1.06 to 1.69 95.4 1.29 1.05 to 1.59
Education Higher education 99.3 96.5 95.6
Lower education 98.6 0.48 0.34 to 0.67 94.5 0.62 0.53 to 0.72 94.0 0.72 0.62 to 0.84
Healthcare experience No 98.9 95.3 94.6
Yes 99.5 2.37 1.57 to 3.56 96.9 1.52 1.28 to 1.81 96.0 1.38 1.18 to 1.61
Variable Characteristics Bipolar disorder Anxiety Addiction
% OR 99% CI % OR 99% CI % OR 99% CI
Gender Women 93.6 91.4 90.0
Men 87.3 0.47 0.42 to 0.53 89.4 0.79 0.71 to 0.89 84.4 0.60 0.54 to 0.67
Other/undisclosed 93.7 1.01 0.39 to 2.60 95.2 1.88 0.64 to 5.55 90.5 1.05 0.48 to 2.31
Age (years) >60 88.9 89.0 86.6
41–60 94.6 2.17 1.90 to 2.49 92.6 1.54 1.37 to 1.74 89.8 1.37 1.23 to 1.52
<40 93.8 1.90 1.59 to 2.26 92.1 1.44 1.23 to 1.70 90.6 1.50 1.29 to 1.74
Education Higher education 94.0 91.6 90.0
Lower education 87.0 0.42 0.38 to 0.47 89.1 0.75 0.67 to 0.84 85.0 0.63 0.57 to 0.69
Healthcare experience No 90.0 90.2 86.0
Yes 94.7 2.00 1.76 to 2.28 92.0 1.25 1.11 to 1.40 92.4 1.97 1.77 to 2.20
Variable Characteristics Stroke Parkinson’s disease Migraine
% OR 99% CI % OR 99% CI % OR 99% CI
Gender Women 89.9 86.9
Men 82.4 0.53 0.48 to 0.58 84.3 0.81 0.73 to 0.89 83.5
Other/undisclosed 89.7 0.98 0.46 to 2.08 84.9 0.85 0.45 to 1.62 79.7 0.78 0.71 to 0.85
Age (years) >60 87.7 86.1 77.6
41–60 89.3 1.16 1.04 to 1.29 87.5 1.13 1.25 to 1.02 86.0 1.78 1.62 to 1.95
<40 84.5 0.76 0.67 to 0.87 83.2 0.80 0.71 to 0.91 88.3 2.18 1.91 to 2.48
Education Higher education 88.3 87.9 84.3
Lower education 86.7 0.87 0.79 to 0.96 82.1 0.63 0.57 to 0.69 78.6 0.69 0.63 to 0.75
Healthcare experience No 84.5 83.1 79.5
Yes 93.0 2.44 2.18 to 2.73 90.9 2.04 1.85 to 2.26 87.2 1.76 1.61 to 1.92
Variable Characteristics Cancer Hypertension Diabetes
% OR 99% CI % OR 99% CI % OR 99% CI
Gender Women 33.8 33.7 16.7
Men 27.9 0.76 0.70 to 0.82 26.5 0.71 0.66 to 0.77 13.8 0.80 0.73 to 0.88
Other/undisclosed 37.3 1.16 0.72 to 1.88 41.3 1.38 0.86 to 2.20 25.4 1.70 1.00 to 2.89
Age (years) >60 28.5 34.2 15.3
41–60 34.1 1.30 1.21 to 1.40 31.5 0.88 0.82 to 0.95 17.2 1.15 1.05 to 1.27
<40 38.2 1.55 1.41 to 1.70 25.4 0.65 0.59 to 0.72 14.7 0.96 0.84 to 1.09
Education Higher education 34.2 33.5 17.3
Lower education 27.7 0.74 0.68 to 0.79 27.9 0.77 0.71 to 0.83 12.8 0.70 0.64 to 0.77
Healthcare experience No 27.4 24.9 10.6
Yes 39.7 1.74 1.63 to 1.87 42.6 2.24 2.09 to 2.39 24.3 2.71 2.49 to 2.96
Variable Characteristics Arthritis
% OR 99% CI
Gender Women 5.1
Men 3.9 0.75 0.63 to 0.89
Other/undisclosed 6.3 1.25 0.49 to 3.23
Age (years) >60 4.5
41–60 5.2 1.15 0.98 to 1.35
<40 4.6 1.01 0.81 to 1.25
Education Higher education 4.9
Lower education 4.6 0.94 0.80 to 1.11
Healthcare experience No 3.4
Yes 7.0 2.12 1.83 to 2.46

Univariate OR and 99% CI.

% indicates proportion of participants rating this disorder or disease as ‘associated with the brain’, with the remainder of participants rating it as ‘not associated with the brain’.

AD, Alzheimer’s disease.