Table 4.

Subgroup Analysis^a for CVD Risk Factors and All-Cause Mortality; Adjusted Hazard Ratios for People With HIV Compared With People Without HIV, With 95% CIs Presented

Sub-groups	Hypertension	Type 2 Diabetes	Chronic Kidney Disease	All-Cause Mortality
Sex
Male	1.42 (1.25–1.61)**	1.33 (1.09–1.61)**	2.60 (2.03–3.32)**	2.88 (2.46–3.37)**
Female	1.28 (1.05–1.56)*	1.13 (0.85–1.51)	2.10 (1.50–2.95)**	2.91 (2.20–3.85)**
Age
<40 years	1.57 (1.27–1.93)**	1.22 (0.85–1.76)	4.67 (2.54–8.58)**	6.73 (4.91–9.21)**
≥40 years	1.34 (1.18–1.52)**	1.29 (1.08–1.54)**	2.28 (1.84–2.81)**	2.27 (1.94–2.66)**
Ethnicity
Non-Whiteb	1.37 (1.22–1.66)**	1.23 (0.94–1.61)	1.56 (1.04–2.36)*	3.44 (2.35–5.03)**
White	1.28 (1.07–1.52)**	1.16 (0.87–1.53)	2.88 (2.09–3.98)**	2.33 (1.85–2.94)**
Deprivation
Most deprived	1.32 (1.05–1.66)*	1.27 (0.92–1.76)	1.71 (1.07–2.72)*	2.45 (1.85–3.23)**
Least deprived	1.11 (0.76–1.62)	1.72 (1.04–2.87)*	2.29 (1.29–4.04)**	4.85 (3.12–7.54)**
Body Mass Index
Obese	1.10 (0.87–1.39)	1.03 (0.79–1.35)	2.17 (1.42–3.30)**	2.07 (1.41–3.05)**
Not Obese	1.38 (1.20–1.59)**	1.46 (1.16–1.85)**	2.33 (1.81–3.00)**	2.95 (2.49–3.49)**
Smoker Status
Current or ex-smoker	1.19 (1.00–1.42)*	1.27 (0.99–1.63)	2.77 (2.05–3.76)**	2.68 (2.23–3.21)**
Never smoked	1.54 (1.33–1.78)**	1.32 (1.06–1.65)*	2.17 (1.64–2.88)**	2.70 (2.12–3.43)**
Index Year
2000–2009	1.34 (1.17–1.53)**	1.40 (1.14–1.71)**	2.08 (1.63–2.65)**	2.75 (2.33–3.25)**
2010–2019	1.45 (1.21–1.75)**	1.09 (0.84–1.42)	3.35 (2.37–4.74)**	3.01 (2.37–3.82)**

Abbreviations: CI, confidence interval; CVD, cardiovascular disease; HIV, human immunodeficiency virus.

^aAdjusted for age, body mass index, sex, smoking status, ethnicity, deprivation, index year, and events at baseline.

^bNon-White subgroup includes people that identify as Black, Asian, mixed, or other.

*P < .05.

**P < .01.