Table 4.
Association of ESR1 polymorphisms with adiposity and dyslipidemia
| SNP | Effect allele | Other allele | Location | Beta | 95% CI | P-value | Adjusted P-value | na | |
|---|---|---|---|---|---|---|---|---|---|
| Weight | rs11968025 | T | G | chr6:151847839 | 0.28 | 0.22-0.35 | 2.5e-17 | 1.0e-16 | 360 116 |
| Weight | rs3853252 | G | A | chr6:151849112 | 0.28 | 0.22-0.35 | 2.2e-17 | 8.8e-17 | 354 838 |
| Body fat distribution (trunk fat ratio), females | rs2982708 | T | C | chr6:152035085 | 0.025 | 0.019-0.031 | 1.0e-14 | 4.0e-14 | 116 138 |
| Total cholesterol | rs4870044 | C | T | chr6:151580274 | 0.013 | 0.0085-0.017 | 2.0e-9 | 8-0e-9 | 297 824 |
Abbreviation: SNP, single nucleotide polymorphism.
aNumber of subjects in analysis.