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. 2020 Nov 11;225(8):1424–1434. doi: 10.1093/infdis/jiaa699

Table 1.

Cox Proportional Hazard Model to Determine Impact of Long-Lasting Insecticidal Net/Insecticidal Exposure on Survival of Field-Caught Anopheles gambiae Sensu Lato 72 Hours After Exposurea

Insecticide Exposure No. (No. of Events) HRR (95% CI) P Valueb
Untreated netting Reference
 PermaNet 2.0 (deltamethrin only) 1135 (1047) 1.095 (.968–1.239) .15
 PermaNet 3.0 side panels (deltamethrin only) 1157 (1088) 0.9664 (.9092–1.027) .27
 PermaNet 3.0 roof panels (PBO + deltamethrin) 563 (533) 1.007 (.939–1.079) .85
Acetone control Reference
 Alpha-cypermethrin 1× 676 (641) 1.006 (.9696–1.043) .77
 Deltamethrin 1× 683 (645) 0.9942 (.9539–1.036) .78
 Permethrin 1× 693 (661) 1.015 (.9698–1.062) .52
 Clothianidin 1× 698 (581) 1.208 (.9227–1.581) .17
 Chlorfenapyr 1× 708 (580) 1.692 (1.086–2.637) .02
 PBO + deltamethrin 1× 630 (577) 0.9662 (.2411–3.873) .96
 Alpha-cypermethrin 5× 633 (601) 0.9951 (.9407–1.053) .86
 Deltamethrin 5× 652 (610) 0.9942 (.9393–1.052) .84
 Permethrin 5× 636 (583) 0.9931 (.8638–1.142) .92
 Alpha-cypermethrin 10× 624 (587) 0.9951 (.917–1.08) .91
 Deltamethrin 10× 623 (588) 0.9943 (.9072–1.09) .90
 Permethrin 10× 656 (603) 1.026 (.9509–1.107) .51
 1× Insecticide dose Reference
 Alpha-cypermethrin 5× 117 (92) 1.016 (.9069–1.138) .78
 Alpha-cypermethrin 10× 108 (78) 1.007 (.9403–1.078) .84
 Deltamethrin 5× 143 (105) 1.0 (.9035–1.107) >.99
 Deltamethrin 10× 114 (83) 1.0 (.9363–1.068) >.99
 Permethrin 5× 137 (94) 1.022 (.8528–1.225) .81
 Permethrin 10× 157 (114) 0.9952 (.9491–1.044) .84

Abbreviations: CI, confidence interval; HRR, hazard rate ratio (ratio of hazard rate for control/reference group to hazard rate for treatment group; PBO, piperonyl butoxide.

aImmediate mortality rates after long-lasting insecticidal net (60 minutes and 24 hours) or insecticidal exposure (30 or 60 minutes, depending on insecticide) were excluded.

bSignificance cutoff level defined as α = .05.