Figure 2.
(A) Volcano plot showing differentially expressed genes (DEGs) between cord blood from mothers with early pregnancy anemia compared to controls. All genes showing FDR < 0.05 are presented in green. DEGs showing logFC > 1.5 are presented in orange. DEGs with FDR < 0.05 and log FC > 1 are presented in red while those with FDR < 0.005 and logFC > 1 are labeled. (B) The expression of LCORL, NMD3 and NCBP1 genes was upregulated in umbilical cord blood from offspring of mothers with early pregnancy anemia compared to controls. (C) cg12884187 and (D) cp06549407 DNAm negatively correlated with LCORL expression (E) cg12884187 DNAm correlated with maternal HB levels in early pregnancy (F) cg06549407 DNAm correlated positively with delivery length (G) LCORL expression correlated with delivery length.