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. 2022 Jan 11;107(5):1294–1302. doi: 10.1210/clinem/dgac011

Table 2.

Baseline characteristics of the 99 individuals of African descent

Characteristics Women P Men P
Risk allele carriers Nonrisk homozygotes Risk allele carriers Nonrisk homozygotes
No. 27 32 24 16 .22
Age, y 43.48 ± 2.21 43.97 ± 1.87 .87 42.54 ± 2.30 45.33 ± 2.42 .42
Disease state
 Hypertensive (n) 18 24 .57 15 11 .75
 Normotensive (n) 9 8 9 5
BMI 29.26 ± 1.00 27.92 ± 0.92 .33 29.20 ± 0.86 28.20 ± 0.90 .42
SBP on LIB diet, mm Hg 140 ± 5 143 ± 4 .63 137 ± 4 138 ± 5 .44
DBP on LIB diet, mm Hg 83 ± 3 83 ± 2 .90 81 ± 2 81 ± 11 .94
Aldosterone on LIB diet, ng/dL 3.70 ± 0.42 4.82 ± 0.62 .04 3.56 ± 0.29 5.63 ± 1.25 .20
PRA on LIB diet, ng/mL/h 0.29 ± 0.06 0.35 ± 0.07 .69 0.31 ± 0.07 0.24 ± 0.05 .96
ARR on LIB diet, ng/dL per ng/mL/h 38.43 ± 11.59 30.50 ± 6.36 .64 21.98 ± 3.81 42.15 ± 17.17 .21
24-h urine sodium excretion on LIB diet, mmol/24 h 215.29 ± 18.20 206.25 ± 15.32 .70 245.78 ± 12.01 208.63 ± 21.93 .90
24-h urine sodium excretion on RES diet, mmol/24 h 19.06 ± 3.83 15.88 ± 1.97 .91 20.93 ± 3.11 18.26 ± 2.61 .99

Data represent mean ± SEM. T test, Wilcoxon rank sum test, or Fisher exact test was used in the analysis.

Abbreviations: ARR, aldosterone-to-renin ratio; BMI, body mass index; DBP, diastolic blood pressure; LIB, liberal salt; PRA, plasma renin activity; RES, restricted salt; SBP, systolic blood pressure.