Figure 1.

Relationship between homeostatic model assessment of beta-cell function (HOMA-2B) and first- phase insulin response at each study timepoint. The relationships between HOMA-2B and first-phase insulin response (by intravenous glucose tolerance test) prepregnancy (A), in early pregnancy (B), and late pregnancy (C) are shown. Panel D shows the change in HOMA-2B across pre-, early, and late pregnancy timepoints. The mean at each timepoint is plotted; the error bars depict the standard error of the mean.