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. 2022 May 3;19(3):339–349. doi: 10.21873/cgp.20324

Figure 2. Effects of GSK-J4 treatment on enrichment of MGMT, TRA2A, U2AF1, RPS6KA2 genes in vivo. (a) PC3-luc, (b) DU-145-luc and (c) LNCaP-luc xenografts treated with GSK-J4 (green bar) and untreated (black bar) were subjected to ChIP qPCR analysis of H3K27me3 enrichment on control genes (Myoglobin and GAPDH) and candidate genes (MGMT, TRA2A, U2AF1, RPS6KA2). Results are represented as fold enrichment over IgG. Values=mean±SD and data were analyzed by unpaired non-parametric test, the Mann-Whitney t-test (*p<0.05).

Figure 2