Figure 3. Effects of GSK-J4 treatment on MGMT, TRA2A, U2AF1, RPS6KA2 expression and candidate oncogenes and oncosupressor expression. mRNA level analysis of candidate genes from PC3-luc, DU-145-luc and LNCaP-luc xenografts were quantified by RT-qPCR using comparative 2(–∆∆Ct) method. Values are the average (mean±SD) from n=8 PC3-luc xenografts, n=7 DU-145-luc xenografts, n=4 LNCaP-luc xenografts and normalized to control xenografts without treatment. Data were analyzed by unpaired t-test to compare gene expression (*p<0.05).
