TABLE 1.
MICs and effects of sub-MIC of various antibiotics on bacterial motility
| Antibiotic | MIC (mg/liter) for:
|
Motility inhibitiona (%)
|
||
|---|---|---|---|---|
| P. mirabilis | P. aeruginosa | P. mirabilis | P. aeruginosa | |
| ERY | 512 | 128 | 94 ± 1.3b | 32 ± 1.6b |
| CLR | 256 | 64 | 98 ± 0.7b | 24 ± 3.0b |
| AZM | 128 | 128 | 84 ± 2.2b | 83 ± 2.5b |
| ROM | 256 | 256 | 0 | 0 |
| CHL | 256 | 16 | 33 ± 2.6b | 12 ± 5.1b |
| GEN | 2 | 1 | 0 | 2 ± 0.6 |
| TET | 64 | 8 | 0 | 0 |
| MIN | 16 | 16 | 0 | 0 |
a
Results are expressed as percent of inhibition of the circular zone of growth on soft agar plates containing 0.25 times the MICs of antibiotics (means ± standard deviations of three experiments).
b
The Student t test was used to determine differences between each value and its mean. A significant difference was seen between this treatment and the control (P < 0.05).