Table 1. Optimization of the Reaction Conditions^a.

entry	c(CiVCPO) (nM)	pH	c(H2O2) (mM)	concn (mM)	initial rateb (mM h–1)	TONc	selectivityd (%)
1	100	5	30	10.3 ± 1.1	3.80	10,2700	99
2	200	5	30	14.6 ± 1.6	5.68	73,200	99
3	400	5	30	24.6 ± 1.2	6.97	61,600	97
4	400	4	30	10.9 ± 1.9	2.95	27,100	96
5	400	6	30	19.6 ± 1.0	6.49	48,880	96
6	400	7	30	12.3 ± 0.1	4.03	30,600	94
7	400	5	50	23.5 ± 5.7	6.36	58,700	98
8	400	5	100	19.4 ± 0.4	3.14	48,000	98
9	400	5	200	21.6 ± 3.5	5.76	54,000	98
10	400	5	100e	26.0 ± 0.7	7.95	65,000	97

^aReaction conditions: [p-coumaric acid] = 30 mM, citrate buffer (100 mM, pH 4–5) or NaPi buffer (100 mM, pH 6−7), [CiVCPO] = 100–400 nM, [KBr] = 50–100 mM, [H₂O₂] = 30–200 mM, 30 °C, 5% DMSO, 6 h, 1 mL.

^bThe initial rate is based on concentration of 1b at 3 h.

^cTON = Turnover number ([1b]/[CiVCPO]).

^dThe selectivity was determined by gas chromatography–mass spectrometry (GC–MS). Selectivity = [1b]/([1b] + [1c]) × 100%.

^e[KBr] = 100 mM. A duplicate experiment was performed.