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. 2014 Aug 15;2014(8):CD005355. doi: 10.1002/14651858.CD005355.pub5

Sinha 2005.

Methods Single centre study
 Allocation by computer‐generated random numbers
 Unblinded
 Power calculation: not performed
 8.3% (4/48) patients excluded because of difficulties which led to them receiving the treatment of the intervention arm and not the control arm as randomised
 Intention‐to‐treat analysis: not performed
 Source of funding: not mentioned
Participants Setting: private endoscopy centre, Mumbai, India
 Inclusion criteria: uterus larger than 12 weeks on bimanual examination, ultrasound confirmation of presence of at least one myoma 7 cm or greater and/or presence of three or more myomas greater than 5 cm in size
Exclusion criteria: submucosal myoma, associated ovarian lesions or other pathology discovered by ultrasound exam, a history of surgery
 n = 48
 Mean age: 32.95 years (SD 4.65) in treatment arm and 33.8 years (SD 6.35) in control arm
 Ethnicity: not described
 Sizes of myomas: the mean size of the myoma was 7.6 cm (SD 4.2) in treatment arm and 7.6 cm (SD 4. 5) in the control arm
Interventions Treatment arm (n = 24): enucleation of myoma by morcellation while still attached to uterus
 Control arm (n = 20): conventional technique of complete enucleation followed by morcellation
 Type of operation: laparoscopy
Outcomes Perioperative blood loss, hospital stay, and length of surgery
 Perioperative blood loss estimated by consistently sucking the blood into a suction bottle without any irrigation until the intracorporeal suturing was completed and the haemostasis confirmed
Notes Indications for myomectomy: symptomatic myomas
Authors not contacted
Risk of bias
Bias Authors' judgement Support for judgement
Random sequence generation (selection bias) Low risk Allocation by computer‐generated random numbers
Allocation concealment (selection bias) Low risk Adequate
Incomplete outcome data (attrition bias) 
 All outcomes High risk 8.3% (4/48) patients excluded because of difficulties which led to them receiving the treatment of the intervention arm and not the control arm as randomised.
Selective reporting (reporting bias) Unclear risk We do not have access to the study protocol
Other bias Low risk No other sources of bias identified
Blinding of participants and personnel (performance bias) 
 All outcomes High risk Unblinded
Blinding of outcome assessment (detection bias) 
 All outcomes High risk Unblinded