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. 2014 Aug 15;2014(8):CD005355. doi: 10.1002/14651858.CD005355.pub5

Behdad 2013.

Trial name or title The effect of infusion of vitamin C during myomectomy on the blood loss during the procedure and postoperative pain
Methods Randomised placebo controlled clinical trial
Participants Inclusion criteria: women with American Society of Anesthesia (ASA) physical status I or II who are candidate for elective abdominal myomectomy, age 25‐40 years old, BMI <35
Exclusion criteria: patients with mental impairment, chronic pain, BMI>35, a history of coagulopathy, psychiatric disease, addiction were excluded
Interventions Intervention 1: Infusion of 3 gr vitamin C in 500 ml normal saline during the surgery
Intervention 2: Infusion of 500 ml normal saline without vitamin C during the surgery
Outcomes Primary Outcome(s): uterine bleeding. Timepoint: during the surgery. Method of measurement: ml blood loss
Secondary Outcome(s): postoperative pain. Timepoint: 1, 6, 12 and 24 hours after the operation. Method of measurement: VAS Score
Starting date October 2012
Contact information Dr Shekoufeh Behdad, Shahid Sadoughi Hospital Yazd, Iran
Notes