Figure 6.

Cortex and telencephalic hemispheres tagged by Neurod1^CreER(D1B)

(A) P7 cortical sections stained for nls-βGAL. Subplate neurons in the sublayer VIb are labeled at TM11.5–TM12.5 (arrowheads). Later TM injections label only a small number of neurons in the layers V and VI. Scale bar, 200 μm.

(B–D) mGFP staining of telencephalic sections prepared from P7 mice tagged at TM12.5 (B), TM13.5 (C), and TM14.5 (D). In (B), the labeling at the bottom (arrowheads) and the top (arrows) of the cortical plate corresponds to the typical positions of basal dendrites and axons of surviving subplate neurons. During later TM stages (C and D), the tagged neurons are concentrated on the medial cortical areas (arrows), and their axons selectively project to the medial part of the striatum (arrowheads). Scale bar, 500 μm.