Table 1.
Summary of KRAS neoantigens detected by targeted MS
| HLA-I | KRAS mutation | Peptide | Peptide length | Reference |
|---|---|---|---|---|
| A∗03:01 | wild-type | ∗VVVGAGGVGK | 10 | this article |
| G12C | VVVGACGVGK | 10 | this article | |
| G12D | VVVGADGVGK | 10 | Wang et al. (2019) and this article | |
| G12R | VVVGARGVGK | 10 | Bear et al. (2021) (9mer) and this article (10mer) | |
| G12V | ∗VVVGAVGVGK | 10 | Douglass et al. (2021) and this article | |
| G12V | ∗VVGAVGVGK | 9 | Douglass et al. (2021) and this article | |
| A∗11:01 | G12C | VVVGACGVGK | 10 | this article |
| G12D | VVVGADGVGK | 10 | Wang et al. (2016) and this article | |
| G12R | VVVGARGVGK | 10 | Bear et al. (2021) (9mer) and this article (10mer) | |
| G12V | ˆVVVGAVGVGK | 10 | Wang et al. (2016) and this article | |
| G12V | VVGAVGVGK | 9 | Wang et al. (2016) and this article | |
| A∗30:01 | G12R | VVVGARGVGK | 10 | this article |
| G12R | VVGARGVGK | 9 | this article | |
| G12V | VVVGAVGVGK | 10 | this article | |
| G12V | VVGAVGVGK | 9 | this article | |
| A∗68:01 | G12C | VVVGACGVGK | 10 | this article |
| G12D | VVVGADGVGK | 10 | this article | |
| G12R | VVVGARGVGK | 10 | this article | |
| G12V | VVVGAVGVGK | 10 | this article | |
| G12V | VVGAVGVGK | 9 | this article | |
| B∗07:02 | G12D | GADGVGKSAL | 10 | Bear et al. (2021) and this article |
| G12R | GARGVGKSAL | 10 | Bear et al. (2021) and this article | |
| C∗01:02 | G12V | AVGVGKSAL | 9 | this article |
| C∗03:03 | G12V | GAVGVGKSAL | 10 | this article |
| G12V | GAVGVGKSA | 9 | this article | |
| C∗03:04 | G12C | GACGVGKSA | 9 | this article |
| G12D | GADGVGKSAL | 10 | this article | |
| G12V | GAVGVGKSAL | 10 | this article | |
| G12V | GAVGVGKSA | 9 | this article | |
| C∗08:02 | G12D | GADGVGKSAL | 10 | Tran et al. (2016) and this article |
| G12D | GADGVGKSA | 9 | Tran et al. (2016) and this article |
KRAS G12C/D/R/V neoantigens detected by PRM in this article as well as those reported in other publications are indicated (first report referenced). Peptides detected in the NCH-H44I cell line are marked with (∗), and the peptide detected in the SW620 cell line is marked with (ˆ).