TABLE 2.
Depletion of MurC impairs ceftriaxone resistance
Strainb | Ceftriaxone MIC (μg/mL)a |
||
---|---|---|---|
NaNO3 (mM) | |||
2 | 5 | 12 | |
Wild-type/vector | 128 | 128 | 128 |
ΔmurC/PnisA-murC | 2 | 4 | 8 |
Minimal inhibitory concentration for ceftriaxone was determined at various levels of MurC induction. Data represent the median MIC from four independent biological replicates.
Strains analyzed were wild-type/vector, OG1/pJLL286; and ΔmurC/PnisA-murC, JL657/pJLL297.