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. 2022 Mar 8;204(4):e00602-21. doi: 10.1128/jb.00602-21

TABLE 2.

Depletion of MurC impairs ceftriaxone resistance

Strainb Ceftriaxone MIC (μg/mL)a
NaNO3 (mM)
2 5 12
Wild-type/vector 128 128 128
ΔmurC/PnisA-murC 2 4 8
a

Minimal inhibitory concentration for ceftriaxone was determined at various levels of MurC induction. Data represent the median MIC from four independent biological replicates.

b

Strains analyzed were wild-type/vector, OG1/pJLL286; and ΔmurC/PnisA-murC, JL657/pJLL297.