TABLE 1.
Susceptibility profiles of amphotericin B against Aspergillus section Terrei in RPMI 1640 and AM3a
| Species (no. of isolates) | RPMI 1640 |
AM3 |
||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MIC (mg/L)b |
MFC (mg/L) |
MIC (mg/L) |
MFC (mg/L) |
|||||||||
| Range | MIC50 | MIC90 | Range | MFC50 | MFC90 | Range | MIC50 | MIC90 | Range | MFC50 | MFC90 | |
| A. section Terrei (100)c | 0.5−16 | 2 | 4 | >16 | >16 | >16 | 1−>16 | 8 | 16 | 4−>16 | 16 | >16 |
| A. terreus s.s. (78) | 0.5-4 | 2 | 4 | >16 | >16 | >16 | 1−>16 | 8 | 16 | 4−>16 | 16 | >16 |
| A. hortai (10) | 0.5−2 | 1 | 2 | >16 | >16 | >16 | 4−16 | 8 | 16 | 4−>16 | 16 | >16 |
| A. citrinoterreus (11) | 1−16 | 2 | 8 | >16 | >16 | >16 | 4−16 | 8 | 16 | 4−>16 | 16 | >16 |
| A. alabamensis (1) | 1 | >16 | 8 | 8 | ||||||||
a
AM3, antibiotic medium 3; MFC, minimum fungicidal concentration; s.s., sensu stricto.
b
MIC50, MIC90, MFC50, and MFC90 are only shown for species with 10 or more isolates.
c
Isolate S164 (susceptible control) is not included in this table.