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. 2022 Apr 5;9:874254. doi: 10.3389/fnut.2022.874254

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Copyright © 2022 Dasdelen, Er, Kaplan, Celik, Beker, Orhan, Tuzcu, Sahin, Mamedova, Sylla, Komorowski, Ojalvo, Sahin and Kilic.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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L-Theanine and Mg-L-theanine compounds increase sleep duration and de-crease sleep latency. Effects of L-theanine and Mg-T compounds on sleep duration (A) and sleep latency (B) after pentobarbital administration. The same test was applied in the caffeine-induced sleep disturbance model (C,D). ANOVA with Tukey’s HSD was performed for multiple comparisons and values are represented as mean ± SD. *p < 0.05: compared to control, ^#p < 0.05: compared to caffeine control, ^$p < 0.05: compared to L-theanine, ^¥p < 0.05: compared to Mg-T1.