TABLE 1.
Partial differentially expressed genes in Δtat
| No. | Gene ID | Fold change (Δtat/WT) | P value | FDR | Gene name | Description | Function |
|---|---|---|---|---|---|---|---|
| 1 | PPECC33_RS16300 | 115.360 | 3.15E-33 | 3.17E-31 | kpsT | ABC transporter ATP-binding protein | Capsular polysaccharide biosynthesis |
| 2 | PPECC33_RS16295 | 40.224 | 4.71E-70 | 3.48E-67 | HAD-IA family hydrolase | ||
| 3 | PPECC33_RS16305 | 36.504 | 5.56E-40 | 8.21E-38 | kpsM | ABC transporter permease | |
| 4 | PPECC33_RS16290 | 31.779 | 2.63E-49 | 7.46E-47 | Hypothetical protein | ||
| 5 | PPECC33_RS16280 | 17.388 | 1.96E-20 | 1.06E-18 | Hypothetical protein | ||
| 6 | PPECC33_RS16275 | 16.912 | 5.47E-35 | 6.21E-33 | Nucleotidyltransferase family protein | ||
| 7 | PPECC33_RS16245 | 16.912 | 2.53E-42 | 4.66E-40 | kpsF | KpsF/GutQ family sugar-phosphate isomerase | |
| 8 | PPECC33_RS16285 | 11.472 | 3.79E-29 | 3.11E-27 | Glycosyltransferase family 2 protein | ||
| 9 | PPECC33_RS16250 | 11.314 | 1.69E-30 | 1.47E-28 | kpsE | Capsule polysaccharide transporter | |
| 10 | PPECC33_RS16255 | 10.056 | 3.08E-30 | 2.62E-28 | kpsD | Polysaccharide biosynthesis/export family protein | |
| 11 | PPECC33_RS16270 | 8.754 | 9.30E-19 | 4.48E-17 | kpsS | Capsular biosynthesis protein | |
| 12 | PPECC33_RS16265 | 7.945 | 4.89E-31 | 4.42E-29 | kpsC | Capsular polysaccharide biosynthesis protein | |
| 13 | PPECC33_RS16260 | 6.364 | 4.14E-20 | 2.21E-18 | kpsU | 3-Deoxy-manno-octulosonate cytidylyltransferase | |
| 14 | PPECC33_RS10985 | 2.346 | 0.000169 | 0.000959 | wzy | O11 family O-antigen polymerase | |
| 15 | PPECC33_RS10950 | 2.293 | 6.53E-07 | 6.77E-06 | manC | Mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase | |
| 16 | PPECC33_RS10940 | 2.219 | 9.50E-08 | 1.19E-06 | cpsG | Colanic acid biosynthesis phosphomannomutase CpsG | |
| 17 | PPECC33_RS10945 | 2.071 | 1.23E-05 | 9.69E-05 | wcaE | Glycosyltransferase | |
| 18 | PPECC33_RS08185 | 17.509 | 9.76E-06 | 7.82E-05 | ydeO | Acid stress response transcriptional regulator YdeO | Stress response |
| 19 | PPECC33_RS07220 | 5.315 | 0.000105 | 0.00064 | yciH | Stress response translation initiation inhibitor YciH | |
| 20 | PPECC33_RS08195 | 3.837 | 2.65E-07 | 3.01E-06 | ydeP | Acid resistance putative oxidoreductase YdeP | |
| 21 | PPECC33_RS12175 | 2.621 | 1.99E-09 | 3.33E-08 | elaB | Stress response protein ElaB | |
| 22 | PPECC33_RS17710 | 2.549 | 3.38E-12 | 8.26E-11 | yhcN | Peroxide/acid stress response protein YhcN | |
| 23 | PPECC33_RS16005 | 2.445 | 1.14E-06 | 1.12E-05 | yggT | Osmotic shock tolerance protein YggT | |
| 24 | PPECC33_RS05995 | 2.219 | 1.08E-05 | 8.59E-05 | bhsA | Multiple stress resistance protein BhsA | |
| 25 | PPECC33_RS22830 | 105.420 | 1.41E-09 | 2.47E-08 | ghoT | Type V toxin-antitoxin system toxin GhoT | Toxin-antitoxin system |
| 26 | PPECC33_RS22825 | 22.785 | 3.52E-06 | 3.12E-05 | ghoS | Type V toxin-antitoxin system endoribonuclease antitoxin GhoS | |
| 27 | PPECC33_RS01555 | 5.657 | 0.00019 | 0.001056 | yafO | Type II toxin-antitoxin system mRNA interferase toxin YafO | |
| 28 | PPECC33_RS03050 | 3.655 | 0.009247 | 0.028521 | hokE | Type I toxin-antitoxin system toxin HokE | |
| 29 | PPECC33_RS01550 | 2.395 | 0.004016 | 0.014354 | yafN | Type I toxin-antitoxin system antitoxin YafN | |
| 30 | PPECC33_RS24555 | 2.238 | 0.002638 | 0.010115 | lsoB | Type II toxin-antitoxin system antitoxin LsoB | |
| 31 | PPECC33_RS07745 | 0.363 | 1.37E-08 | 2.03E-07 | hokB | Type I toxin-antitoxin system toxin HokB | |
| 32 | PPECC33_RS24945 | 0.409 | 8.06E-07 | 8.20E-06 | Type I toxin-antitoxin system Hok family toxin | ||
| 33 | PPECC33_RS06820 | 0.432 | 6.95E-06 | 5.78E-05 | hokD | Type I toxin-antitoxin system toxin HokD | |
| 34 | PPECC33_RS00080 | 0.473 | 5.55E-07 | 5.87E-06 | mokC | Type I toxin-antitoxin system toxin MokC | |
| 35 | PPECC33_RS00280 | 0.480 | 0.001035 | 0.004596 | Type II toxin-antitoxin system CcdA family antitoxin | ||
| 36 | PPECC33_RS27840 | 0.490 | 0.01337 | 0.038627 | Type I toxin-antitoxin system toxin Ldr family protein |