Table 1.
Characteristics of healthy donors and B‐NHL patients
| Groups | Healthy individuals | BNHL | BNHL‐ND | BNHL‐Remission | BNHL‐Relapsed |
|---|---|---|---|---|---|
| Average age (range) | 51.13 (27–75) | 57.55 (23–85) | 61.74 (23–82) | 54.36 (31–79) | 58.35 (23–85) |
| Gender, number | |||||
| Female | 8 | 35 | 7 | 22 | 6 |
| Male | 7 | 66 | 12 | 23 | 28 |
| Lymphoma type, number | |||||
| CLL | ‐ | 12 | 1 | 4 | 5 |
| DLBCL | ‐ | 48 | 10 | 18 | 17 |
| HGBL | ‐ | 14 | 4 | 10 | 0 |
| MCL | ‐ | 12 | 1 | 3 | 8 |
| MZL | ‐ | 10 | 1 | 7 | 2 |
| PCNSL | ‐ | 4 | 0 | 3 | 1 |
| FL | ‐ | 1 | 0 | 0 | 1 |
| B syndromes, number | ‐ | ||||
| No | ‐ | 49 | 11 | 26 | 11 |
| Yes | ‐ | 49 | 8 | 16 | 23 |
| LDH levels, number (U/L) | ‐ | ||||
| <120 | ‐ | 8 | 0 | 5 | 3 |
| 120–250 | ‐ | 71 | 13 | 30 | 26 |
| >250 | ‐ | 21 | 6 | 9 | 5 |
| IPI score, number | ‐ | ||||
| 0 | ‐ | 11 | 1 | 9 | 1 |
| 1 | ‐ | 19 | 3 | 10 | 6 |
| 2 | ‐ | 20 | 2 | 10 | 7 |
| 3 | ‐ | 22 | 4 | 6 | 12 |
| 4 | ‐ | 8 | 3 | 0 | 4 |
| 5 | ‐ | 6 | 3 | 1 | 4 |
| Ann Arbor stage, number | ‐ | ||||
| I | ‐ | 2 | 1 | 0 | 1 |
| II | ‐ | 13 | 3 | 9 | 1 |
| III | ‐ | 10 | 2 | 3 | 4 |
| IV | ‐ | 54 | 8 | 22 | 22 |
Abbreviations: B‐NHL, B‐cell non‐Hodgkin's lymphoma; B symptoms, B symptoms refer to systemic symptoms of fever, night sweats, and weight loss which can be associated with B‐NHL; CLL, chronic lymphocytic leukemia; DLBDL, diffuse large B‐cell lymphoma; FL, follicular lymphoma; G‐MDSC, granulocyte MDSC; HDs, healthy donors; HGBL, high‐grade B‐cell lymphoma; IPI, International Prognostic Index; LDH, lactate dehydrogenase; MCL, Mantle‐cell lymphoma; MDSC, myeloid‐derived suppressor cells; M‐MDSC, monocyte MDSC; MZL, marginal zone Lymphoma; ND, newly diagnosed patients with B‐NHL; PCNSL, primary central nervous system lymphoma.