Table 5.

A review on peptide sequences under investigation for entry inhibition of SARS-CoV-2 virus

Target protein	Target domain	Name	Sequence	References
Spike protein	RBD	P4	EEQAKTFLDKFN	Han et al. (2006)
			HEAEDLFYQSS
Spike protein	RBD	P5	EEQAKTFLDKFNH	Han et al. (2006)
			EAEDLFYQSSLA
Spike protein	RBD	P6	YQDVNCTDVS(P)	Han et al. (2006)
			TAIHADQLTP
Spike protein	RBD	AHB1	DEDLEELERLYRKAE	Cao et al. (2020)
			EVAKEAKDASRRGD
			DERAKEQMERAMRLF
			DQVFELAQELQE
			KQTDGNRQKATHLDKA
			VKEAADELYQR
			VRELEEQVMHVLDQVSEL
			AHELLHKLT
			GEELERAAYFNWWATEMML
			ELIKSDDEREIREIEEEAR
			RILEHLEELARK
Spike protein	RBD	AHB2	ELEEQVMHVLDQVSEL	Cao et al. (2020)
			AHELLHKLTGEELERAAYFNWWATEMMLE
			LIKSDDEREIREIEEEARRILEHLEELARK
Spike protein	RBD	LCB1	DKEWILQKIYEIMRLLDELGHAEASMRVSDLIYEF	Cao et al. (2020)
			MKKGDERLLEEAERLLEEVER
Spike protein	RBD	LCB3	NDDELHMLMTDLVYEALHFAKDEEIKKRVFQLFE	Cao et al. (2020)
			LADKAYKNNDRQKLEKVVEELKELLERLLS
ACE2	RBD Binding site	SP-4	GFLYVYKGYQPI	Ho et al. (2006)
ACE2	RBD Binding site	SP-8	FYTTTGIGYQPY	Ho et al. (2006)
ACE2	RBD Binding site	SP-10	STSQKSIVAYTM	Ho et al. (2006)
Furin	Catalytic domain	dec-RVKR-cmk	dec-RVKR-cmk	Hoffmann et al. (2020b)
Furin	Catalytic domain	MI-1851	(S)-N-((S)-1-((4-Carbamimidoylbenzyl)amino)-4-(guanidinooxy)-1-oxobutan-2-yl)-2-((S)-2-(2-(4-(guanidinomethyl)phenyl)acetamido)-4-(guanidinooxy)butanamido)-3,3-dimethylbutanamide	Bestle et al. (2020)
TMPRSS2	Catalytic site	MI-432	(S)-3-(3-(4-(2-Aminoethyl)piperidin-1-yl)-2-((2′,4′-dichloro-[1,1′-biphenyl])-3-sulfonamido)-3-oxopropyl)benzimidamide	Meyer et al. (2013)
TMPRSS2	Catalytic site	MI-1900	(S)-4-(3-(3-Carbamimidoylphenyl)-2-((2′,4′-dimethoxy-[1,1′-biphenyl])-3-sulfonamido)propanoyl)-N-cyclohexylpiperazine-1-carboxamide	Meyer et al. (2013)
Cathepsin L	Acidification	P9	NGAICWGPCPTAFRQJGNCGHFKVRCCKIR	Zhao et al. (2020)
Cathepsin L	Acidification	P9R	NGAICWGPCPTAFRQJGNCGRFRVRCCRIR	Zhao et al. (2020)
Cathepsin L	Acidification	8P9R	8 × NGAICWGPCPTAFRQJGNCGRFRVRCCRIR	Zhao et al. (2021)