Table 2.

Plasma Levels of Active Compounds

Treatment group	Atomoxetine (n = 9)		Paroxetine (n = 10)a		Total venlafaxine and ODV (n = 10)
Dose level	Plasma level mean (ng/mL ± SD)	Plasma level range (ng/mL)	Plasma level mean (ng/mL ± SD)	Plasma level range (ng/mL)	Plasma level mean (ng/mL ± SD)	Plasma level range (ng/mL)
I	114 (70)	33–235	17 (15)	0–52	101 (69)	0–224
II	106 (50)	0–160	38 (20)	10–66	242 (115)	107–497
III	198 (90)	50–462	61 (22)	33–91	376 (143)	164–580
IV	184 (101)	54–325	81(28)	40–119	472 (243)	159–849

Abbreviation: ODV, O-desmethyl-venlafaxine.

^a Data for 1 patient not included due to a detection issue (see results section).