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Superimposed distances (in Angstroms) between the acceptor oxygen (O) of M217 and donor nitrogen (ND1) of catalytic site residue H209 in (MMP1 Zn1 Zn2) (red), (MMP1 Zn1) (blue), (MMP1 Zn2) (yellow), and (MMP1 no Zn) (green). Hydrogen bond formation takes place when both of the Zn(II) ions are removed from the system, which may alter the structural orientation of the catalytic site.
