Table 2.

The result of dsDNA, IL-17, IL-6, IL-23, and Treg expression on Healthy, Placebo, Steroid, and Nigella sativa L. group.

Groups	n	dsDNA		p-value
		$\overline{\text{x}}$± SD	Min-Max
Healthy	10	45.32 ± 2.56a	41.36–47.88	<0.001∗
Placebo	10	57.88 ± 0.84b	56.12–58.87
Steroid	10	52.86 ± 1.80c	50.99–55.91
Nigella sativa L.	10	49.01 ± 1.17d	48.03–50.71
		IL-17
		$\overline{\text{x}}$± SD	Min-Max
Healthy	10	0,89 ± 0,52a	0.19–1.52	<0.001∗
Placebo	10	2.51 ± 0.72b	1.73–3.73
Steroid	10	1.39 ± 0.27c	0.85–1.76
Nigella sativa L.	10	0.97 ± 0.31d	0.71–1.53
		IL-6
		$\overline{\text{x}}$± SD	Min-Max
Healthy	10	0.21 ± 0.09a	0.09–0.34	<0.001∗
Placebo	10	2.39 ± 0.50b	2.03–3.59
Steroid	10	0.49 ± 0.07c	0.38–0.59
Nigella sativa L.	10	0.29 ± 0.06d	0.21–0.39
		IL-23
		$\overline{\text{x}}$± SD	Min-Max
Healthy	10	1.59 ± 0.51a	0.73–2.33	<0.001∗
Placebo	10	5.17 ± 0.39b	4.68–5.87
Steroid	10	3.20 ± 0.59c	2.36–4.35
Nigella sativa L.	10	1.60 ± 0.57d	0.92–2.38
		Treg
		$\overline{\text{x}}$± SD	Min-Max
Healthy	10	217.9 ± 52.0a	144.9–290.6	<0.001∗
Placebo	10	99,528.76 ± 56,395.11b	16,136.30–186,255.76
Steroid	10	314,182.38 ± 119,942.73c	135,804.19–483,868.47
Nigella sativa L.	10	229,322.63 ± 54,432.00d	149,168.74–326,112.20

∗dsDNA: Kruskal-Wallis test, significant if α < 0.05; a,b,c,d Superscript showed the significant difference between the treatment group (Mann-Whitney U test); IL17:Kruskal-Wallis test, significant if α < 0.05; a,b,c,d Superscript showed the significant difference between the treatment group (Mann-Whitney U test); IL6:Kruskal-Wallis test, significant if α < 0.0; a,b,c,d Superscript showed the significant difference between the treatment group (Mann-Whitney U test); IL23:OnewayAnova, significant if α < 0.05; a,b,c Superscript showed the significant difference between treatment group of LSD multiple comparisons; Treg: Kruskal-Wallis test, significant if p = 0.05; a,b,c,d Superscript showed there is a significant difference among the treatment groups (multiple comparisons Games-Howell).