Table 2.
Characteristics of NOMAS participants, overall and stratified by ILAS status
| Characteristic | All n=1109 |
Non-ILAS n=1028 |
ILAS n=81 |
P-value |
|---|---|---|---|---|
| Age, mean (SD) (years) | 70.4 (8.8) | 70.2 (8.7) | 74.0 (9.2) | <0.001 |
| Men, N (%) | 439 (39.6) | 402 (39.1) | 37 (45.7) | 0.24 |
| Ethnicity | 0.01 | |||
| NH White, N (%) | 154 (13.9) | 145 (14.1) | 9 (11.1) | |
| Hispanic, N (%) | 771 (69.5) | 722 (70.2) | 49 (60.45) | |
| NH Black, N (%) | 184 (16.6) | 161 (15.7) | 23 (28.4) | |
| Hypertension, N (%) | 877 (79.1) | 802 (78.0) | 75 (92.6) | 0.01 |
| Diabetes, N (%) | 289 (26.1) | 258 (25.1) | 31 (38.3) | 0.01 |
| Dyslipidemia, N (%) | 993 (89.5) | 920 (89.5) | 73 (90.1) | 0.86 |
| Statin therapy, N (%) | 279 (25.2) | 251 (24.4) | 28 (34.6) | 0.04 |
| Current smoking, N (%) | 130 (11.7) | 123 (12.0) | 7 (8.6) | 0.37 |
| History of MI, stent or CABG, N (%) | 269 (24.3) | 247 (24.0) | 22 (27.2) | 0.53 |
| History of atrial fibrillation, N (%) | 44 (4) | 36 (3.5) | 8 (9.9) | 0.01 |
| MAF | ||||
| ADIPOQ rs2241767 (G) | 0.22 | 0.22 | 0.09 | <0.001 |
| ADIPOQ rs182052 (A) | 0.37 | 0.37 | 0.38 | 0.75 |
| RNF213 rs112735431 (A) | 0 | 0 | 0 | - |
| APOE rs429358 (C) | 0.09 | 0.09 | 0.11 | 0.37 |
| PDE4D rs2910829 (A) | 0.52 | 0.52 | 0.47 | 0.21 |
| LPL rs320 (G) | 0.28 | 0.28 | 0.31 | 0.44 |
| CYP11B2 rs1799998 (G) | 0.37 | 0.37 | 0.28 | 0.02 |
Abbreviations: CABG, coronary artery bypass graft; MAF, minor allele frequencies; MI, myocardial infarction; NH, non-Hispanic; SD, standard deviation.
Chi-squared test for categorical variables and t test for continuous variables.
Bold values indicate statistically significant difference with P < 0.05.